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Std: 16mg/250mL = 64 mcg/mL
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About

In critical care settings, vasopressor management requires zero margin for error. Calculating infusion rates (mL/hr) from weight-based dosing (mcg/kg/min) is a frequent task that carries high risk during emergencies. Errors in concentration or conversion can lead to hemodynamic instability.

This tool is designed for ICU nurses and physicians. It includes a verified database of standard concentrations and specific high-dose thresholds. If a calculated rate or entered dose exceeds standard safety protocols, the tool triggers a visual alert, prompting a double-check of the order.

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Formulas

The infusion rate R (mL/hr) is derived from the desired dose D (mcg/kg/min), patient weight W (kg), and drug concentration C (mcg/mL):

R = D × W × 60C

Where 60 converts minutes to hours. If the concentration is in mg/mL, it must first be multiplied by 1000 to match the dose units.

Reference Data

DrugStandard ConcentrationTypical Starting DoseMax Safe Dose (Alert)
Norepinephrine16 mg/250mL (64 mcg/mL)0.05 mcg/kg/min3.0 mcg/kg/min
Epinephrine4 mg/250mL (16 mcg/mL)0.05 mcg/kg/min1.0 mcg/kg/min
Dopamine400 mg/250mL (1600 mcg/mL)5.0 mcg/kg/min20.0 mcg/kg/min
Phenylephrine40 mg/250mL (160 mcg/mL)0.5 mcg/kg/min5.0 mcg/kg/min
Vasopressin20 units/100mL (0.2 units/mL)0.03 units/min0.04 units/min

Frequently Asked Questions

Yes. For drugs like Vasopressin which are dosed in units/min (flat dose), the weight parameter is excluded from the calculation logic automatically.
The result box will flash red and display a warning message. This indicates the calculated dose exceeds typical maximums found in critical care literature. It does not prevent the calculation but serves as a mandatory pause point for verification.
Yes. While the dropdown provides standard hospital concentrations (e.g., 'Quad strength'), you can manually override the final concentration field (mcg/mL) to match your specific pharmacy preparation.