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About

Pulmonary Embolism (PE) presents a diagnostic challenge in emergency medicine due to its variable clinical presentation. The Wells Criteria serves as a validated risk stratification tool to determine the pre-test probability of PE. By categorizing patients into risk groups, clinicians can standardize the decision to pursue D-dimer testing or proceed directly to CT Pulmonary Angiography (CTPA). This tool automates the scoring process, reducing cognitive load during critical assessment phases.

Misdiagnosis of PE carries severe consequences, including mortality from untreated embolism or complications from unnecessary anticoagulation. Conversely, overuse of imaging exposes patients to radiation and contrast nephropathy. Accurate risk stratification balances these concerns. This calculator utilizes the traditional point system, where specific clinical signs carry weighted integer values.

clinical calculator pulmonary embolism wells score medical risk assessment d-dimer

Formulas

The Wells Score is calculated by summing the weights of present clinical features:

Score = 7i=1 wi

Where w represents the weight of each positive criterion:

  • Clinical signs of DVT: +3.0
  • Alternative diagnosis less likely than PE: +3.0
  • Heart Rate > 100: +1.5
  • Immobilization or Surgery: +1.5
  • Previous PE/DVT: +1.5
  • Hemoptysis: +1.0
  • Malignancy: +1.0

Reference Data

Risk CategoryScore RangeClinical Probability (Incidence)Recommended Action
Low Risk0 to 11.3% to 12%Consider D-dimer (High Sensitivity)
Moderate Risk2 to 616% to 28%D-dimer or CTA depending on sensitivity
High Risk> 637.5% to 60%CT Pulmonary Angiography (CTA)
PE Unlikely (Simplified) 412%High Sensitivity D-dimer
PE Likely (Simplified)> 437%Diagnostic Imaging

Frequently Asked Questions

The Wells Criteria is most effective when applied to patients presenting with symptoms suspicious for PE (dyspnea, chest pain) in an emergency or outpatient setting. It should be used before imaging to guide the diagnostic pathway (e.g., deciding whether a D-dimer is sufficient to rule out PE).
The Wells Criteria risk-stratifies patients who are suspected of having a PE. The PERC (Pulmonary Embolism Rule-out Criteria) rule is a separate tool used specifically for patients already deemed "Low Risk" by clinical gestalt or Wells score, to avoid D-dimer testing entirely.
No. The criterion "Alternative diagnosis less likely than PE" requires significant clinical judgment. This calculator aids in standardizing the scoring but relies on the physician's accurate assessment of the patient's presentation.
The Three-Tier model classifies risk as Low, Moderate, or High. The Two-Tier model simplifies this into "PE Unlikely" (Score 0-4) and "PE Likely" (Score > 4). Both interpretations are provided in the results of this tool.