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About

In critical care settings, accurate medication delivery is a matter of life and death. Nurses and pharmacists must frequently convert a prescribed dose (e.g., mcg/kg/min) into the volumetric flow rate (mL/hr) that can be programmed into an electronic infusion pump. Errors in this calculation can lead to dangerous overdoses or ineffective therapy.

This tool streamlines the process by integrating a database of standard concentrations for common vasoactive and sedative drugs. It handles the dimensional analysis automatically, converting between mass units (mcg, mg, g) and time units (min, hr), ensuring that the final pump setting accurately reflects the physician's order.

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Formulas

The core formula utilizes dimensional analysis to cancel out mass and time units, leaving volume per time.

Rate (mL/hr) = Dose × Weight × 60Concentration

Where Concentration is total drug mass divided by total volume, converted to the same mass unit as the dose (e.g., mcg/mL).

Reference Data

DrugStandard Conc.Typical Dose RangeCalculation Type
Norepinephrine4mg / 250mL0.01 3.0 mcg/kg/minWeight-based
Dopamine400mg / 250mL2 20 mcg/kg/minWeight-based
Propofol1000mg / 100mL5 50 mcg/kg/minWeight-based
Amiodarone900mg / 500mL1 mg/minNon-weight-based
Insulin (Regular)100units / 100mL1 10 units/hrFixed Rate

Frequently Asked Questions

Yes. If the prescription is in mg/min or mcg/min rather than mcg/kg/min, simply enter "1" in the weight field or use the "Non-weight based" toggle if available, effectively removing mass from the equation.
The calculator automatically normalizes units. If your bag is in mg but the dose is in mcg, the tool multiplies the bag mass by 1000 internally to match the dose unit before calculating the rate.
No. This is a double-check tool. Always prioritize the "Guardrails" or drug library built into your facility's smart infusion pumps, as they contain specific hospital protocols and hard limits.
The "Standard Concentration" dropdown pre-fills the fields for convenience, but the "Amount" and "Volume" fields are fully editable. You must always verify the physical bag in your hand matches the numbers on screen.