User Rating 0.0
Total Usage 1 times
Total mg taken so far:
Current Daily Dose (mg):
Is this tool helpful?

Your feedback helps us improve.

About

Achieving a specific cumulative dose is the primary predictor of long-term remission in acne treatment with Isotretinoin. Stopping treatment simply because skin clears is a common error. This often leads to relapse. Clinical guidelines typically recommend a target range of 120 to 150 mg/kg body weight.

This dashboard helps patients and clinicians visualize the trajectory of the therapy. It tracks the milligrams ingested to date against the patient's weight. It then projects the completion date based on the current daily maintenance dose.

dermatology accutane calculator acne treatment isotretinoin dosage cumulative dose

Formulas

The Cumulative Dose Dcum is the ratio of total drug ingested Mtotal to patient weight W.

Dcum = MtotalW

The Remaining Dose Mrem is the target T minus Mtotal. The Days Remaining t is found by dividing by the daily dose d.

t = (T × W) Mtotald

Reference Data

Patient Weight (kg)Target Lower (120mg/kg)Target Upper (150mg/kg)Avg Duration (at 40mg/day)
506,000 mg7,500 mg~5-6 Months
607,200 mg9,000 mg~6-7 Months
708,400 mg10,500 mg~7-8 Months
809,600 mg12,000 mg~8-10 Months
9010,800 mg13,500 mg~9-11 Months

Frequently Asked Questions

Isotretinoin works on accumulation. not daily timing. If you miss a dose. do not double up. Simply continue. The missed dose will just push your estimated finish date back by one day.
Studies have shown that patients who reach a cumulative threshold of 120mg/kg have significantly lower relapse rates than those who stop earlier. Some protocols now suggest going as high as 220mg/kg for severe cases.
Yes. The target is weight-dependent. If your weight changes significantly (e.g. >5kg) during the 6-month course. you should recalculate your target total.