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About

Risk stratification in multimorbid patients requires quantifying the cumulative burden of disease. The Charlson Comorbidity Index (CCI) assigns integer weights to specific clinical conditions based on their association with mortality. Age acts as a multiplier in this system, acknowledging that physiological reserve diminishes over time.

This tool streamlines the scoring process for clinicians. It aggregates weights from 19 specific conditions and an age-adjustment factor. The resulting score correlates with 10-year survival probability. High scores indicate a need for adjusted therapeutic targets, careful surgical risk assessment, and potentially palliative care planning rather than aggressive intervention.

survival analysis geriatrics mortality risk CCI score medical calculator

Formulas

The total score S is the summation of weighted comorbidities plus the age factor.

S = wi + AgeScore

Age Weights:

  • < 50 years: 0 points
  • 50-59 years: 1 point
  • 60-69 years: 2 points
  • 70-79 years: 3 points
  • ≥ 80 years: 4 points

Reference Data

CCI Score10-Year Survival (P)Risk Level
098%Low
196%Low
290%Moderate
377%Moderate
453%High
521%Very High
6< 2%Critical

Frequently Asked Questions

A solid tumor receives 2 points. However, if the tumor is metastatic, it is scored as a separate category worth 6 points. Do not score both for the same primary malignancy unless distinct pathologies exist.
The original Charlson index does not include uncomplicated hypertension. It focuses on end-organ damage or systemic conditions like Congestive Heart Failure or Cerebrovascular Disease.
While validated primarily in hospital cohorts, the CCI is widely used in outpatient settings and insurance actuarial tables to predict resource utilization and long-term prognosis.