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About

Isotretinoin (Accutane) therapy relies on reaching a specific cumulative dosage to minimize the risk of acne relapse. Dermatologists typically aim for a total range of 120 mg to 150 mg per kilogram of body weight over the course of treatment. This calculator helps patients and providers track progress toward this goal. By inputting the daily dosage and treatment duration, it visualizes exactly how far along the patient is, helping to estimate the remaining time needed to complete the course.

accutane isotretinoin acne dermatology medical calculator cumulative dose

Formulas

The cumulative dose is the sum of all medication taken divided by body weight.

Cum. Dose = Daily Dose × DaysWeight (kg)

The goal is:

120 Cum. Dose 150

Reference Data

Patient WeightMin Target (120mg/kg)Max Target (150mg/kg)Avg Duration (40mg/day)
50 kg (110 lbs)6,000 mg7,500 mg5 - 6 Months
60 kg (132 lbs)7,200 mg9,000 mg6 - 7 Months
70 kg (154 lbs)8,400 mg10,500 mg7 - 8 Months
80 kg (176 lbs)9,600 mg12,000 mg8 - 10 Months
90 kg (198 lbs)10,800 mg13,500 mg9 - 11 Months

Frequently Asked Questions

Clinical studies have shown that patients who reach a cumulative dose of at least 120mg/kg have significantly lower relapse rates compared to those who stop earlier, even if their skin looks clear.
Missing a single dose is usually not critical. The therapy is about the total accumulation over months, not daily precision. Simply continue as prescribed; do not double dose to catch up.